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Variant (rsID / SNP)

rs397516834

SDHB

rs397516834 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to SDHB. Location: chromosome 1, position 17,355,103. Clinical significance in the table: Conflicting interpretations of pathogenicity.

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Reference-table entries

SDHBConflicting interpretations
Clinical significance (as recorded)
Conflicting interpretations of pathogenicity
Variant type
single nucleotide variant
Chromosome / position
1:17355103
Cytoband
1p36.13
HGVS
NM_003000.3(SDHB):c.415C>T (p.Leu139Phe)
Allele change
Missense_L139F

Associated conditions / phenotypes

Hereditary cancer-predisposing syndrome

Public references

Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.