Variant (rsID / SNP)
rs121913529
rs121913529 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to KRAS. Location: chromosome 12, position 25,398,284. Clinical significance in the table: Pathogenic.
Reference-table entries
- Clinical significance (as recorded)
- Pathogenic
- Variant type
- single nucleotide variant
- Chromosome / position
- 12:25398284
- Cytoband
- 12p12.1
- HGVS
- NM_004985.5(KRAS):c.35G>A (p.Gly12Asp)
- Allele change
- Missense_G12A
Associated conditions / phenotypes
Carcinoma of pancreas|Neoplasm of stomach|Epidermal nevus|Nevus sebaceous|Linear nevus sebaceous syndrome|Juvenile myelomonocytic leukemia|Autoimmune lymphoproliferative syndrome type 4|Non-small cell lung carcinoma|Neoplasm of ovary|Neoplasm of the large intestine|Lung carcinoma|Acute myeloid leukemia|Thyroid tumor|RASopathy|Cerebral arteriovenous malformation|Vascular Tumors Including Pyogenic Granuloma|Primary low grade serous adenocarcinoma of ovary|Capillary malformation-arteriovenous malformation 1|Encephalocraniocutaneous lipomatosis
Public references
Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.