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Variant (rsID / SNP)

rs121907900

WT1

rs121907900 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to WT1. Location: chromosome 11, position 32,413,566. Clinical significance in the table: Pathogenic.

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Reference-table entries

WT1Pathogenic
Clinical significance (as recorded)
Pathogenic
Variant type
single nucleotide variant
Chromosome / position
11:32413566
Cytoband
11p13
HGVS
NM_024426.6(WT1):c.1399C>T (p.Arg467Trp)
Allele change
Missense_R450W

Associated conditions / phenotypes

Drash syndrome|Nephrotic syndrome, type 4|Meacham syndrome|Drash syndrome|Wilms tumor 1|11p partial monosomy syndrome|Frasier syndrome|Steroid-resistant nephrotic syndrome|Nephrotic range proteinuria|Wilms tumor 1

Public references

Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.