Variant (rsID / SNP)
rs121434569
rs121434569 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to EGFR. Location: chromosome 7, position 55,249,071. Clinical significance in the table: drug response.
Reference-table entries
EGFRDrug response
- Clinical significance (as recorded)
- drug response
- Variant type
- single nucleotide variant
- Chromosome / position
- 7:55249071
- Cytoband
- 7p11.2
- HGVS
- NM_005228.5(EGFR):c.2369C>T (p.Thr790Met)
- Allele change
- Missense_T745M
Associated conditions / phenotypes
Nonsmall cell lung cancer, resistance to tyrosine kinase inhibitor in|Tyrosine kinase inhibitor response|Non-small cell lung carcinoma|erlotinib response - Efficacy|Lung carcinoma|EGFR-related lung cancer|Hereditary cancer-predisposing syndrome|gefitinib response - Efficacy|Lung cancer
Public references
Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.