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Gene entry

EGFR

epidermal growth factor receptor

Chromosome
7
Cytoband
7p11.2
Variants (rsID)
54

EGFR is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 7 (region 7p11.2). Its official name is “epidermal growth factor receptor”. The reference table lists 54 variants (rsID) for this gene.

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Clinically classified variants

7 reference-table entries with clinical significance.

  • rs2072454Benignsingle nucleotide variantEGFR-related lung cancer|Inflammatory skin and bowel disease, neonatal, 2
  • rs2293347Benignsingle nucleotide variantEGFR-related lung cancer
  • rs712830Benignsingle nucleotide variant
  • rs121434568Drug responsesingle nucleotide variantAdenocarcinoma of lung, response to tyrosine kinase inhibitor in, somatic|Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, somatic|Tyrosine kinase inhibitor response|gefitinib response - Efficacy|Lung adenocarcinoma|Non-small cell lung carcinoma|Lung carcinoma|Gefitinib response|Erlotinib response
  • rs121434569Drug responsesingle nucleotide variantNonsmall cell lung cancer, resistance to tyrosine kinase inhibitor in|Tyrosine kinase inhibitor response|Non-small cell lung carcinoma|erlotinib response - Efficacy|Lung carcinoma|EGFR-related lung cancer|Hereditary cancer-predisposing syndrome|gefitinib response - Efficacy|Lung cancer
  • rs144496976Uncertain significancesingle nucleotide variantHereditary cancer|EGFR-related lung cancer
  • rs11979255Not classifiedintron_variant

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.