Variant (rsID / SNP)
rs11554290
rs11554290 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to NRAS. Location: chromosome 1, position 115,256,529. Clinical significance in the table: Pathogenic.
Reference-table entries
- Clinical significance (as recorded)
- Pathogenic
- Variant type
- single nucleotide variant
- Chromosome / position
- 1:115256529
- Cytoband
- 1p13.2
- HGVS
- NM_002524.5(NRAS):c.182A>G (p.Gln61Arg)
- Allele change
- Missense_Q61R
Associated conditions / phenotypes
Thyroid cancer, nonmedullary, 2|Epidermal nevus|Non-small cell lung carcinoma|Large congenital melanocytic nevus|Neurocutaneous melanocytosis|Linear nevus sebaceous syndrome|Renal cell carcinoma, papillary, 1|B-cell chronic lymphocytic leukemia|Melanoma|Neoplasm of brain|Lung adenocarcinoma|Adrenal cortex carcinoma|Ovarian serous cystadenocarcinoma|Malignant melanoma of skin|Nasopharyngeal neoplasm|Hepatocellular carcinoma|Multiple myeloma|Gastric adenocarcinoma|Neoplasm of the large intestine|Glioblastoma|Acute myeloid leukemia|Transitional cell carcinoma of the bladder|Malignant neoplasm of body of uterus
Public references
Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.