Variant (rsID / SNP)
rs876659802
rs876659802 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to TP53. Location: chromosome 17, position 7,577,105. Clinical significance in the table: Conflicting interpretations of pathogenicity.
Reference-table entries
- Clinical significance (as recorded)
- Conflicting interpretations of pathogenicity
- Variant type
- single nucleotide variant
- Chromosome / position
- 17:7577105
- Cytoband
- 17p13.1
- HGVS
- NM_000546.6(TP53):c.833C>T (p.Pro278Leu)
- Allele change
- Missense_P146L
Associated conditions / phenotypes
Hereditary cancer-predisposing syndrome|Malignant neoplasm of body of uterus|Neoplasm of the large intestine|Neoplasm of brain|Breast neoplasm|Squamous cell carcinoma of the skin|Carcinoma of esophagus|Lung adenocarcinoma|Ovarian serous cystadenocarcinoma|Malignant melanoma of skin|Squamous cell lung carcinoma|Multiple myeloma|Pancreatic adenocarcinoma|Squamous cell carcinoma of the head and neck|Neoplasm of ovary|Li-Fraumeni syndrome|Gallbladder cancer
Public references
Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.