Variant (rsID / SNP)

rs74681492

rs74681492 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to LRRK2. Location: chromosome 12, position 40,704,252. Clinical significance in the table: Likely benign.

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Reference-table entries

LRRK2Likely benign

Clinical significance (as recorded): Likely benign
Variant type: single nucleotide variant
Chromosome / position: 12:40704252
Cytoband: 12q12
HGVS: NM_198578.4(LRRK2):c.4337C>T (p.Pro1446Leu)
Allele change: Missense_P1446L

Associated conditions / phenotypes

Autosomal dominant Parkinson disease 8

Public references

dbSNP
ClinVar
Ensembl
gnomAD

Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.