Variant (rsID / SNP)
rs4149056
rs4149056 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to SLCO1B1. Location: chromosome 12, position 21,331,549. Clinical significance in the table: drug response.
Reference-table entries
SLCO1B1Drug response
- Clinical significance (as recorded)
- drug response
- Variant type
- single nucleotide variant
- Chromosome / position
- 12:21331549
- Cytoband
- 12p12.1
- HGVS
- NM_006446.5(SLCO1B1):c.521T>C (p.Val174Ala)
- Allele change
- Missense_V174A
Associated conditions / phenotypes
Rotor syndrome|simvastatin acid response - Metabolism/PK|Gilbert syndrome|simvastatin response - Toxicity|hmg coa reductase inhibitors response - Toxicity|atorvastatin response - Toxicity|rosuvastatin response - Metabolism/PK|atorvastatin response - Metabolism/PK
Public references
Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.