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Variant (rsID / SNP)

rs33995463

LRRK2

rs33995463 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to LRRK2. Location: chromosome 12, position 40,629,436. Clinical significance in the table: Conflicting interpretations of pathogenicity.

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Reference-table entries

LRRK2Conflicting interpretations
Clinical significance (as recorded)
Conflicting interpretations of pathogenicity
Variant type
single nucleotide variant
Chromosome / position
12:40629436
Cytoband
12q12
HGVS
NM_198578.4(LRRK2):c.356T>C (p.Leu119Pro)
Allele change
Missense_L119P

Associated conditions / phenotypes

Autosomal dominant Parkinson disease 8

Public references

Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.