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Variant (rsID / SNP)

rs186641437

APC

rs186641437 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to APC. Location: chromosome 5, position 112,173,765. Clinical significance in the table: Uncertain significance.

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Reference-table entries

APCUncertain significance
Clinical significance (as recorded)
Uncertain significance
Variant type
single nucleotide variant
Chromosome / position
5:112173765
Cytoband
5q22.2
HGVS
NM_000038.6(APC):c.2474A>G (p.Tyr825Cys)
Allele change
Missense_Y825C

Associated conditions / phenotypes

Hereditary cancer-predisposing syndrome|Carcinoma of colon|Desmoid disease, hereditary|Hepatocellular carcinoma|Neoplasm of stomach|Familial adenomatous polyposis 1|Familial adenomatous polyposis 1

Public references

Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.