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Variant (rsID / SNP)

rs1800566

NQO1

rs1800566 is a genetic variant (SNP, identifier in the dbSNP catalogue) that the reference table assigns to NQO1. Location: chromosome 16, position 69,745,145. Clinical significance in the table: Pathogenic; risk factor.

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Reference-table entries

NQO1Pathogenic
Clinical significance (as recorded)
Pathogenic; risk factor
Variant type
single nucleotide variant
Chromosome / position
16:69745145
Cytoband
16q22.1
HGVS
NM_000903.3(NQO1):c.559C>T (p.Pro187Ser)
Allele change
Missense_P153S

Associated conditions / phenotypes

Leukemia, post-chemotherapy, susceptibility to|Breast cancer, post-chemotherapy poor survival in|Benzene toxicity, susceptibility to|Lung carcinoma

Public references

Classifications are reproduced unchanged from the reference table. For education only; not a substitute for medical or genetic counselling.