Gene entry
WWOX
WW domain containing oxidoreductase
- Chromosome
- 16
- Cytoband
- 16q23.1-q23.2
- Variants (rsID)
- 529
WWOX is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 16 (region 16q23.1-q23.2). Its official name is “WW domain containing oxidoreductase”. The reference table lists 529 variants (rsID) for this gene.
Clinically classified variants
19 reference-table entries with clinical significance.
- rs11545029Benignsingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Developmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12|Autosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 28
- rs117065412Benignsingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12|Autosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 28
- rs140817689Benignsingle nucleotide variantAutosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 28
- rs141361080Benignsingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 28|Autosomal recessive spinocerebellar ataxia 12
- rs144601717Benignsingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 28|Autosomal recessive spinocerebellar ataxia 12
- rs200461412Benignsingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12|Autosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 28
- rs2548861Benignsingle nucleotide variantAutosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 1
- rs74944733Benignsingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12|Autosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 28
- rs186745328Conflicting interpretationssingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12
- rs193027041Conflicting interpretationssingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 28
- rs79771882Conflicting interpretationssingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12
- rs368928190Pathogenicsingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12
- rs756762196Pathogenicsingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 28|Autosomal recessive spinocerebellar ataxia 12|Malignant tumor of esophagus|Developmental and epileptic encephalopathy, 28
- rs184773837Uncertain significancesingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12
- rs193001955Uncertain significancesingle nucleotide variantAutosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 1
- rs200699154Uncertain significancesingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12|Autosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 28|Malignant tumor of esophagus|Developmental and epileptic encephalopathy, 28
- rs200839945Uncertain significancesingle nucleotide variantDevelopmental and epileptic encephalopathy, 1|Autosomal recessive spinocerebellar ataxia 12
- rs202006159Uncertain significancesingle nucleotide variantAutosomal recessive spinocerebellar ataxia 12|Developmental and epileptic encephalopathy, 1
- rs383362Not classified3_prime_UTR_variantOsteogenic Sarcoma|Lung Cancer Susceptibility 3|Cervical Cancer|Adenocarcinoma
Other listed variants
- rs377651
- rs389195
- rs415738
- rs494736
- rs719743
- rs924870
- rs954811
- rs1010080
- rs1076600
- rs1078591
- rs1079191
- rs1079572
- rs1106507
- rs1107650
- rs1110434
- rs1110891
- rs1124597
- rs1394568
- rs1543296
- rs1574442
- rs1808447
- rs1862694
- rs1875940
- rs1877275
- rs1978483
- rs1983093
- rs2037961
- rs2075831
- rs2077576
- rs2134993
- rs2178952
- rs2194292
- rs2194340
- rs2202423
- rs2247561
- rs2253016
- rs2278052
- rs2287972
- rs2345443
- rs2472193
- rs2548832
- rs2548876
- rs2550634
- rs2550647
- rs2550655
- rs2550683
- rs2550718
- rs2550731
- rs2656630
- rs2656635
- rs2656652
- rs2656667
- rs2667542
- rs2667627
- rs2737297
- rs2738501
- rs2738553
- rs2738588
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.