Gene entry
WDR35
WD repeat domain 35
- Chromosome
- 2
- Cytoband
- 2p24.1
- Variants (rsID)
- 23
WDR35 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 2 (region 2p24.1). Its official name is “WD repeat domain 35”. The reference table lists 23 variants (rsID) for this gene.
Clinically classified variants
13 reference-table entries with clinical significance.
- rs1056233Benignsingle nucleotide variantShort-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2
- rs1191778Benignsingle nucleotide variantShort-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2|Short-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2
- rs142955097Benignsingle nucleotide variantCranioectodermal dysplasia 2|Short-rib thoracic dysplasia 7 with or without polydactyly|Short-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2|Connective tissue disorder
- rs144493712Benignsingle nucleotide variantShort-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2|Cranioectodermal dysplasia 2|Short-rib thoracic dysplasia 7 with or without polydactyly
- rs56395266Benignsingle nucleotide variantCranioectodermal dysplasia 2|Short-rib thoracic dysplasia 7 with or without polydactyly|Short-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2|Connective tissue disorder
- rs74469198Benignsingle nucleotide variantShort-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2
- rs140308808Conflicting interpretationssingle nucleotide variantCranioectodermal dysplasia 2|Short-rib thoracic dysplasia 7 with or without polydactyly|Short-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2
- rs74470618Conflicting interpretationssingle nucleotide variantCranioectodermal dysplasia 2|Short-rib thoracic dysplasia 7 with or without polydactyly|Short-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2
- rs75602337Conflicting interpretationssingle nucleotide variantShort-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2|Short-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2
- rs139543775Likely benignsingle nucleotide variantCranioectodermal dysplasia 2|Short-rib thoracic dysplasia 7 with or without polydactyly
- rs200042577Likely benignsingle nucleotide variantCranioectodermal dysplasia 2|Short-rib thoracic dysplasia 7 with or without polydactyly|Short-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia 2
- rs267607175Likely pathogenicsingle nucleotide variantCranioectodermal dysplasia 2
- rs199952377Pathogenicsingle nucleotide variantCranioectodermal dysplasia 2|WDR35-Related Disorders|Jeune thoracic dystrophy|Cranioectodermal dysplasia 2|Short-rib thoracic dysplasia 7 with or without polydactyly|Cranioectodermal dysplasia
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.