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Gene entry

USH1C

USH1 protein network component harmonin

Chromosome
11
Cytoband
11p15.1
Variants (rsID)
47

USH1C is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 11 (region 11p15.1). Its official name is “USH1 protein network component harmonin”. The reference table lists 47 variants (rsID) for this gene.

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Clinically classified variants

27 reference-table entries with clinical significance.

  • rs115931035Benignsingle nucleotide variantUsher syndrome type 1C
  • rs142751309Benignsingle nucleotide variant
  • rs2072225Benignsingle nucleotide variantUsher syndrome type 1C|Autosomal recessive nonsyndromic hearing loss 18A
  • rs2237964Benignsingle nucleotide variantAutosomal recessive nonsyndromic hearing loss 18A|Usher syndrome type 1C
  • rs34077456Benignsingle nucleotide variant
  • rs34581703Benignsingle nucleotide variantUsher syndrome type 1C
  • rs35188020Benignsingle nucleotide variantUsher syndrome type 1C
  • rs41282936Benignsingle nucleotide variantUsher syndrome type 1C
  • rs55843567Benignsingle nucleotide variantUsher syndrome type 1C
  • rs75157409Benignsingle nucleotide variantUsher syndrome type 1C
  • rs77137413Benignsingle nucleotide variantUsher syndrome type 1C
  • rs145013633Conflicting interpretationssingle nucleotide variantUsher syndrome type 1C|Autosomal recessive nonsyndromic hearing loss 18A
  • rs146333270Conflicting interpretationssingle nucleotide variantHearing impairment
  • rs146451547Conflicting interpretationssingle nucleotide variantAutosomal recessive nonsyndromic hearing loss 18A|Usher syndrome type 1C|Usher syndrome type 1
  • rs149510892Conflicting interpretationssingle nucleotide variant
  • rs200490320Conflicting interpretationssingle nucleotide variantUsher syndrome type 1C
  • rs202095395Conflicting interpretationssingle nucleotide variantUsher syndrome type 1C
  • rs35336155Conflicting interpretationssingle nucleotide variantUsher syndrome type 1C
  • rs369021714Conflicting interpretationssingle nucleotide variantUsher syndrome type 1C|Autosomal recessive nonsyndromic hearing loss 18A
  • rs41282932Conflicting interpretationssingle nucleotide variantAutosomal recessive nonsyndromic hearing loss 18A|Usher syndrome type 1C|Meniere disease
  • rs778447994Conflicting interpretationssingle nucleotide variantUsher syndrome type 1C
  • rs121908370Pathogenicsingle nucleotide variantUsher syndrome type 1C|Usher syndrome type 1C|Usher syndrome type 1|Autosomal recessive nonsyndromic hearing loss 18A|Autosomal recessive nonsyndromic hearing loss 18A
  • rs1480243085PathogenicDeletionUsher syndrome type 1C|Usher syndrome type 1
  • rs151045328Pathogenicsingle nucleotide variantUsher syndrome type 1C|Usher syndrome type 1|Usher syndrome|Usher syndrome type 1C|Usher syndrome type 1|Autosomal recessive nonsyndromic hearing loss 18A|Rare genetic deafness|Autosomal recessive nonsyndromic hearing loss 18A
  • rs142730611Uncertain significancesingle nucleotide variantUsher syndrome type 1C
  • rs199537187Uncertain significancesingle nucleotide variantUsher syndrome type 1C|Autosomal recessive nonsyndromic hearing loss 18A
  • rs202174251Uncertain significancesingle nucleotide variantUsher syndrome type 1C

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.