Genetics University — Research, Education, Medical Genetics
Knowledge Hub

Gene entry

TXNRD2

thioredoxin reductase 2

Chromosome
22
Cytoband
22q11.21
Variants (rsID)
30

TXNRD2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 22 (region 22q11.21). Its official name is “thioredoxin reductase 2”. The reference table lists 30 variants (rsID) for this gene.

ShareE-MailWhatsAppLinkedInXFacebookTelegram

Clinically classified variants

8 reference-table entries with clinical significance.

  • rs1139793Benignsingle nucleotide variantCardiovascular phenotype|Primary dilated cardiomyopathy|Glucocorticoid deficiency 5
  • rs11541479Benignsingle nucleotide variantCardiovascular phenotype|Primary dilated cardiomyopathy
  • rs5748469Benignsingle nucleotide variantCardiovascular phenotype|Primary dilated cardiomyopathy|Glucocorticoid deficiency 5
  • rs199510610Conflicting interpretationssingle nucleotide variantPrimary dilated cardiomyopathy|Cardiovascular phenotype
  • rs201913959Conflicting interpretationssingle nucleotide variantPrimary dilated cardiomyopathy|Cardiovascular phenotype
  • rs767236339Conflicting interpretationssingle nucleotide variantPrimary familial hypertrophic cardiomyopathy|Cardiovascular phenotype|Primary dilated cardiomyopathy
  • rs201391000Likely benignsingle nucleotide variantCardiovascular phenotype|Primary dilated cardiomyopathy
  • rs201658653Uncertain significancesingle nucleotide variantPrimary dilated cardiomyopathy

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.