Gene entry
TPMT
thiopurine S-methyltransferase
- Chromosome
- 6
- Cytoband
- 6p22.3
- Variants (rsID)
- 57
TPMT is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 6 (region 6p22.3). Its official name is “thiopurine S-methyltransferase”. The reference table lists 57 variants (rsID) for this gene.
Clinically classified variants
7 reference-table entries with clinical significance.
- rs1800462Drug responsesingle nucleotide variantThiopurine methyltransferase deficiency
- rs1800584Drug responsesingle nucleotide variantThiopurine methyltransferase deficiency
- rs74423290Drug responsesingle nucleotide variantThiopurine methyltransferase deficiency
- rs1142345Likely benignsingle nucleotide variantThiopurine methyltransferase deficiency
- rs1800460Likely benignsingle nucleotide variantThiopurine methyltransferase deficiency
- rs2842934Likely benignsingle nucleotide variant
- rs398122996Not classifiedsingle nucleotide variant
Other listed variants
- rs2518463
- rs2842950
- rs3931660
- rs4449636
- rs6921269
- rs9333569
- rs9333570
- rs9477633
- rs12201199
- rs12529220
- rs12663332
- rs17839843
- rs55992000
- rs72552736
- rs72552737
- rs72552738
- rs72552739
- rs72552740
- rs72552742
- rs72556347
- rs77339739
- rs79901429
- rs111901354
- rs112339338
- rs114468543
- rs115106679
- rs116933546
- rs139793761
- rs141028204
- rs144017186
- rs146425737
- rs148885303
- rs150900439
- rs151149760
- rs182021285
- rs199762828
- rs200591577
- rs202034437
- rs267607275
- rs281874771
- rs377085266
- rs543657302
- rs543679347
- rs545492145
- rs548667009
- rs574488518
- rs750424422
- rs772832951
- rs777686348
- rs1183234651
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.