Gene entry
TPH2
tryptophan hydroxylase 2
- Chromosome
- 12
- Cytoband
- 12q21.1
- Variants (rsID)
- 34
TPH2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 12 (region 12q21.1). Its official name is “tryptophan hydroxylase 2”. The reference table lists 34 variants (rsID) for this gene.
Clinically classified variants
6 reference-table entries with clinical significance.
- rs11178998Benignsingle nucleotide variantTryptophan 5-monooxygenase deficiency
- rs4290270Benignsingle nucleotide variantTryptophan 5-monooxygenase deficiency
- rs7305115Benignsingle nucleotide variantTryptophan 5-monooxygenase deficiency
- rs120074175Risk factorsingle nucleotide variantUnipolar depression, susceptibility to
- rs120074176Risk factorsingle nucleotide variantAttention deficit-hyperactivity disorder, susceptibility to, 7
- rs17110563Uncertain significancesingle nucleotide variantBipolar affective disorder, susceptibility to|Tryptophan 5-monooxygenase deficiency
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.