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Gene entry

TMPRSS6

transmembrane serine protease 6

Chromosome
22
Cytoband
22q12.3
Variants (rsID)
33

TMPRSS6 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 22 (region 22q12.3). Its official name is “transmembrane serine protease 6”. The reference table lists 33 variants (rsID) for this gene.

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Clinically classified variants

12 reference-table entries with clinical significance.

  • rs115270691Benignsingle nucleotide variantMicrocytic anemia
  • rs115310908Benignsingle nucleotide variantMicrocytic anemia
  • rs117576908Benignsingle nucleotide variantMicrocytic anemia
  • rs139105452Benignsingle nucleotide variantMicrocytic anemia
  • rs2111833Benignsingle nucleotide variantMicrocytic anemia
  • rs2235321Benignsingle nucleotide variantMicrocytic anemia|Iron-refractory iron deficiency anemia
  • rs4820268Benignsingle nucleotide variantMicrocytic anemia|Iron-refractory iron deficiency anemia
  • rs76970337Benignsingle nucleotide variantMicrocytic anemia
  • rs79816125Benignsingle nucleotide variantMicrocytic anemia
  • rs855791Benignsingle nucleotide variantMicrocytic anemia|Iron-refractory iron deficiency anemia
  • rs185482276Likely benignsingle nucleotide variantMicrocytic anemia
  • rs267607121Pathogenicsingle nucleotide variantIron-refractory iron deficiency anemia

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.