Gene entry
TMEM127
transmembrane protein 127
- Chromosome
- 2
- Cytoband
- 2q11.2
- Variants (rsID)
- 7
TMEM127 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 2 (region 2q11.2). Its official name is “transmembrane protein 127”. The reference table lists 7 variants (rsID) for this gene.
Clinically classified variants
6 reference-table entries with clinical significance.
- rs121908823Benignsingle nucleotide variantPheochromocytoma|Hereditary cancer-predisposing syndrome|Hereditary pheochromocytoma-paraganglioma
- rs200327514Benignsingle nucleotide variantHereditary cancer-predisposing syndrome|Hereditary pheochromocytoma-paraganglioma
- rs750870974Benignsingle nucleotide variantHereditary cancer-predisposing syndrome|Hereditary pheochromocytoma-paraganglioma|Pheochromocytoma
- rs758726687Likely benignsingle nucleotide variantHereditary cancer-predisposing syndrome|Pheochromocytoma|Hereditary pheochromocytoma-paraganglioma
- rs121908830Pathogenicsingle nucleotide variantPheochromocytoma, susceptibility to|Pheochromocytoma|Hereditary cancer-predisposing syndrome|Hereditary pheochromocytoma-paraganglioma
- rs121908824Uncertain significancesingle nucleotide variantPheochromocytoma|Hereditary pheochromocytoma-paraganglioma|Hereditary cancer-predisposing syndrome
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.