Genetics University — Research, Education, Medical Genetics
Knowledge Hub

Gene entry

TMC1

transmembrane channel like 1

Chromosome
9
Cytoband
9q21.13
Variants (rsID)
46

TMC1 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 9 (region 9q21.13). Its official name is “transmembrane channel like 1”. The reference table lists 46 variants (rsID) for this gene.

ShareE-MailWhatsAppLinkedInXFacebookTelegram

Clinically classified variants

8 reference-table entries with clinical significance.

  • rs370898981Conflicting interpretationssingle nucleotide variantRare genetic deafness|Nonsyndromic Hearing Loss, Dominant|Autosomal recessive nonsyndromic hearing loss 7|Autosomal dominant nonsyndromic hearing loss 36
  • rs372710475Conflicting interpretationssingle nucleotide variantRare genetic deafness|Autosomal recessive nonsyndromic hearing loss 7|Autosomal dominant nonsyndromic hearing loss 36|Hearing loss, autosomal recessive
  • rs370088722Likely pathogenicsingle nucleotide variantRare genetic deafness
  • rs121908072Pathogenicsingle nucleotide variantAutosomal dominant nonsyndromic hearing loss 36|Rare genetic deafness
  • rs121908073Pathogenicsingle nucleotide variantAutosomal recessive nonsyndromic hearing loss 7|Rare genetic deafness|Hearing loss, autosomal recessive
  • rs138527651Pathogenicsingle nucleotide variantRare genetic deafness|Autosomal recessive nonsyndromic hearing loss 7
  • rs151001642Pathogenicsingle nucleotide variantRare genetic deafness
  • rs200171616Pathogenicsingle nucleotide variant

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.