Gene entry
SUFU
SUFU negative regulator of hedgehog signaling
- Chromosome
- 10
- Cytoband
- 10q24.32
- Variants (rsID)
- 14
SUFU is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 10 (region 10q24.32). Its official name is “SUFU negative regulator of hedgehog signaling”. The reference table lists 14 variants (rsID) for this gene.
Clinically classified variants
10 reference-table entries with clinical significance.
- rs141950577Benignsingle nucleotide variantGorlin syndrome|Medulloblastoma|Medulloblastoma|Hereditary cancer-predisposing syndrome
- rs189234140Benignsingle nucleotide variantGorlin syndrome|Medulloblastoma|Medulloblastoma|Hereditary cancer-predisposing syndrome
- rs2274351Benignsingle nucleotide variantJoubert syndrome 32|Gorlin syndrome|Gorlin syndrome|Medulloblastoma
- rs35166585Benignsingle nucleotide variantGorlin syndrome|Medulloblastoma|Medulloblastoma|Hereditary cancer-predisposing syndrome
- rs150569584Conflicting interpretationssingle nucleotide variantMedulloblastoma|Hereditary cancer-predisposing syndrome|Medulloblastoma|Gorlin syndrome
- rs34406289Conflicting interpretationssingle nucleotide variantGorlin syndrome|Medulloblastoma|Hereditary cancer-predisposing syndrome
- rs36049457Conflicting interpretationssingle nucleotide variantGorlin syndrome|Medulloblastoma|Hereditary cancer-predisposing syndrome
- rs117196884Likely benignsingle nucleotide variantMedulloblastoma
- rs192025919Uncertain significancesingle nucleotide variantJoubert syndrome 32
- rs201326378Uncertain significancesingle nucleotide variantGorlin syndrome|Medulloblastoma|Hereditary cancer-predisposing syndrome|Gorlin syndrome
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.