Gene entry
SUCLA2
succinate-CoA ligase ADP-forming subunit beta
- Chromosome
- 13
- Cytoband
- 13q14.2
- Variants (rsID)
- 16
SUCLA2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 13 (region 13q14.2). Its official name is “succinate-CoA ligase ADP-forming subunit beta”. The reference table lists 16 variants (rsID) for this gene.
Clinically classified variants
10 reference-table entries with clinical significance.
- rs142020748Benignsingle nucleotide variantMitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
- rs149321505Benignsingle nucleotide variantMitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
- rs57270175Benignsingle nucleotide variantMitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
- rs61756204Benignsingle nucleotide variantMitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
- rs141295770Conflicting interpretationssingle nucleotide variantMitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
- rs200167311Conflicting interpretationssingle nucleotide variantMitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
- rs367890526Conflicting interpretationssingle nucleotide variantMitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
- rs370898100Likely pathogenicsingle nucleotide variant
- rs121908538Pathogenicsingle nucleotide variantMitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
- rs141647723Uncertain significancesingle nucleotide variantMitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.