Gene entry
SPRED1
sprouty related EVH1 domain containing 1
- Chromosome
- 15
- Cytoband
- 15q14
- Variants (rsID)
- 20
SPRED1 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 15 (region 15q14). Its official name is “sprouty related EVH1 domain containing 1”. The reference table lists 20 variants (rsID) for this gene.
Clinically classified variants
9 reference-table entries with clinical significance.
- rs200157475Benignsingle nucleotide variantLegius syndrome|Noonan syndrome and Noonan-related syndrome
- rs8039150Benignsingle nucleotide variantLegius syndrome
- rs115440602Conflicting interpretationssingle nucleotide variantLegius syndrome
- rs147204964Conflicting interpretationssingle nucleotide variantLegius syndrome|Noonan syndrome and Noonan-related syndrome
- rs369711772Conflicting interpretationssingle nucleotide variantLegius syndrome|Noonan syndrome and Noonan-related syndrome
- rs79309779Likely benignsingle nucleotide variantLegius syndrome
- rs121434312Pathogenicsingle nucleotide variantLegius syndrome|Noonan syndrome and Noonan-related syndrome|Neurodevelopmental delay
- rs121434313Pathogenicsingle nucleotide variantLegius syndrome
- rs864622410PathogenicDeletionLegius syndrome|Noonan syndrome and Noonan-related syndrome
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.