Gene entry
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2
- Chromosome
- 14
- Cytoband
- 14q21.3
- Variants (rsID)
- 16
SOS2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 14 (region 14q21.3). Its official name is “SOS Ras/Rho guanine nucleotide exchange factor 2”. The reference table lists 16 variants (rsID) for this gene.
Clinically classified variants
5 reference-table entries with clinical significance.
- rs1014879Benignsingle nucleotide variant
- rs113460230Benignsingle nucleotide variantNoonan syndrome 9|Noonan syndrome and Noonan-related syndrome
- rs137961578Benignsingle nucleotide variantNoonan syndrome 9|Noonan syndrome|Noonan syndrome and Noonan-related syndrome
- rs869320687Pathogenicsingle nucleotide variantNoonan syndrome 9|Noonan syndrome
- rs72681869Uncertain significancesingle nucleotide variant
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.