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Gene entry

SOD1

superoxide dismutase 1

Chromosome
21
Cytoband
21q22.11
Variants (rsID)
13

SOD1 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 21 (region 21q22.11). Its official name is “superoxide dismutase 1”. The reference table lists 13 variants (rsID) for this gene.

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Clinically classified variants

7 reference-table entries with clinical significance.

  • rs80265967Conflicting interpretationssingle nucleotide variantAmyotrophic lateral sclerosis type 1|Amyotrophic lateral sclerosis 1, autosomal recessive|Amyotrophic Lateral Sclerosis, Dominant|Amyotrophic lateral sclerosis
  • rs121912455Likely pathogenicsingle nucleotide variantAmyotrophic lateral sclerosis type 1
  • rs121912438Pathogenicsingle nucleotide variantAmyotrophic lateral sclerosis type 1
  • rs121912441Pathogenicsingle nucleotide variantAmyotrophic lateral sclerosis type 1|Motor neuron disease
  • rs121912442Pathogenicsingle nucleotide variantAmyotrophic lateral sclerosis type 1
  • rs121912443Pathogenicsingle nucleotide variantAmyotrophic lateral sclerosis type 1|Amyotrophic lateral sclerosis
  • rs121912451Pathogenicsingle nucleotide variantAmyotrophic lateral sclerosis type 1

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.