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Gene entry

SMS

spermine synthase

Chromosome
X
Cytoband
Xp22.11
Variants (rsID)
29

SMS is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome X (region Xp22.11). Its official name is “spermine synthase”. The reference table lists 29 variants (rsID) for this gene.

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Clinically classified variants

7 reference-table entries with clinical significance.

  • rs201275730Benignsingle nucleotide variantHistory of neurodevelopmental disorder
  • rs121434610Pathogenicsingle nucleotide variantSyndromic X-linked intellectual disability Snyder type|Inborn genetic diseases
  • rs267607076Pathogenicsingle nucleotide variantSyndromic X-linked intellectual disability Snyder type
  • rs397515381Pathogenicsingle nucleotide variantSyndromic X-linked intellectual disability Snyder type
  • rs397515550Pathogenicsingle nucleotide variantSyndromic X-linked intellectual disability Snyder type
  • rs397515551Pathogenicsingle nucleotide variantSyndromic X-linked intellectual disability Snyder type
  • rs397515549Not classifiedsingle nucleotide variantSyndromic X-linked intellectual disability Snyder type

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.