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Gene entry

SHOC2

SHOC2 leucine rich repeat scaffold protein

Chromosome
10
Cytoband
10q25.2
Variants (rsID)
15

SHOC2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 10 (region 10q25.2). Its official name is “SHOC2 leucine rich repeat scaffold protein”. The reference table lists 15 variants (rsID) for this gene.

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Clinically classified variants

4 reference-table entries with clinical significance.

  • rs1327552Benignsingle nucleotide variantNoonan syndrome-like disorder with loose anagen hair 1
  • rs200015085Conflicting interpretationssingle nucleotide variantRASopathy|Noonan syndrome-like disorder with loose anagen hair 1
  • rs201289608Conflicting interpretationssingle nucleotide variantRASopathy
  • rs267607048Pathogenicsingle nucleotide variantNoonan syndrome-like disorder with loose anagen hair 1|RASopathy|Noonan syndrome|Inborn genetic diseases|Noonan syndrome-like disorder with loose anagen hair|Noonan syndrome and Noonan-related syndrome|Polycystic kidney disease 4

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.