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Gene entry

SERPINE1

serpin family E member 1

Chromosome
7
Cytoband
7q22.1
Variants (rsID)
11

SERPINE1 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 7 (region 7q22.1). Its official name is “serpin family E member 1”. The reference table lists 11 variants (rsID) for this gene.

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Clinically classified variants

5 reference-table entries with clinical significance.

  • rs6090Benignsingle nucleotide variantCongenital plasminogen activator inhibitor type 1 deficiency
  • rs7241Benignsingle nucleotide variantCongenital plasminogen activator inhibitor type 1 deficiency
  • rs7242Benignsingle nucleotide variantCongenital plasminogen activator inhibitor type 1 deficiency
  • rs6092Conflicting interpretationssingle nucleotide variantCongenital plasminogen activator inhibitor type 1 deficiency|Susceptibility to severe coronavirus disease (COVID-19) due to an impaired coagulation process
  • rs2227692Not classifiedintron_variantGastric Cancer|Type 2 Diabetes Mellitus|Microvascular Complications of Diabetes 6|Microvascular Complications of Diabetes 4|Microvascular Complications of Diabetes 3|Microvascular Complications of Diabetes 7

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.