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Gene entry

SCNN1B

sodium channel epithelial 1 subunit beta

Chromosome
16
Cytoband
16p12.2
Variants (rsID)
36

SCNN1B is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 16 (region 16p12.2). Its official name is “sodium channel epithelial 1 subunit beta”. The reference table lists 36 variants (rsID) for this gene.

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Clinically classified variants

5 reference-table entries with clinical significance.

  • rs35731153Conflicting interpretationssingle nucleotide variantBronchiectasis with or without elevated sweat chloride 1|Liddle syndrome 1|Autosomal recessive pseudohypoaldosteronism type 1
  • rs149868979Likely pathogenicsingle nucleotide variantLow renin, low aldosterone hypertension
  • rs137852711Pathogenicsingle nucleotide variantBronchiectasis with or without elevated sweat chloride 1
  • rs13306629Uncertain significancesingle nucleotide variant
  • rs72654338Uncertain significancesingle nucleotide variantBronchiectasis with or without elevated sweat chloride 1

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.