Gene entry
SCN1B
sodium voltage-gated channel beta subunit 1
- Chromosome
- 19
- Cytoband
- 19q13.11
- Variants (rsID)
- 12
SCN1B is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 19 (region 19q13.11). Its official name is “sodium voltage-gated channel beta subunit 1”. The reference table lists 12 variants (rsID) for this gene.
Clinically classified variants
10 reference-table entries with clinical significance.
- rs16969930Benignsingle nucleotide variantCardiovascular phenotype|Generalized epilepsy with febrile seizures plus, type 1|Brugada syndrome 5|Seizure
- rs67701503Benignsingle nucleotide variantBrugada syndrome 5
- rs72558029Benignsingle nucleotide variantLong QT syndrome|Cardiovascular phenotype|Generalized epilepsy with febrile seizures plus, type 1|Seizure|Brugada syndrome 5
- rs150721582Conflicting interpretationssingle nucleotide variantCardiovascular phenotype|Seizure|Brugada syndrome 5
- rs16969926Conflicting interpretationssingle nucleotide variantBrugada syndrome 5
- rs193922728Conflicting interpretationssingle nucleotide variantBrugada syndrome 5|Cardiac arrhythmia
- rs267607028Conflicting interpretationssingle nucleotide variantBrugada syndrome 5
- rs72558026Conflicting interpretationssingle nucleotide variantVentricular fibrillation|Brugada syndrome 5
- rs16969925Pathogenicsingle nucleotide variantAtrial fibrillation, familial, 13|Generalized epilepsy with febrile seizures plus, type 1|Atrial fibrillation, familial, 13|Developmental and epileptic encephalopathy, 52|Brugada syndrome 5|Brugada syndrome 5
- rs180943300Uncertain significancesingle nucleotide variantBrugada syndrome 5|Brugada syndrome 5|Generalized epilepsy with febrile seizures plus, type 1|Atrial fibrillation, familial, 13|Developmental and epileptic encephalopathy, 52
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.