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Gene entry

SCN11A

sodium voltage-gated channel alpha subunit 11

Chromosome
3
Cytoband
3p22.2
Variants (rsID)
26

SCN11A is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 3 (region 3p22.2). Its official name is “sodium voltage-gated channel alpha subunit 11”. The reference table lists 26 variants (rsID) for this gene.

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Clinically classified variants

9 reference-table entries with clinical significance.

  • rs13059805Benignsingle nucleotide variantFamilial episodic pain syndrome with predominantly lower limb involvement|Hereditary sensory and autonomic neuropathy type 7
  • rs150269814Benignsingle nucleotide variantCharcot-Marie-Tooth disease|Hereditary sensory and autonomic neuropathy type 7|Familial episodic pain syndrome with predominantly lower limb involvement
  • rs201111033Benignsingle nucleotide variantFamilial episodic pain syndrome with predominantly lower limb involvement|Hereditary sensory and autonomic neuropathy type 7
  • rs33985936Benignsingle nucleotide variantFamilial episodic pain syndrome with predominantly lower limb involvement|Hereditary sensory and autonomic neuropathy type 7|Hereditary sensory and autonomic neuropathy type 7|Familial episodic pain syndrome with predominantly lower limb involvement
  • rs72869687Benignsingle nucleotide variantFamilial episodic pain syndrome with predominantly lower limb involvement|Hereditary sensory and autonomic neuropathy type 7
  • rs141686175Conflicting interpretationssingle nucleotide variantFamilial episodic pain syndrome with predominantly lower limb involvement|Hereditary sensory and autonomic neuropathy type 7|Familial episodic pain syndrome with predominantly lower limb involvement
  • rs146942592Conflicting interpretationssingle nucleotide variantFamilial episodic pain syndrome with predominantly lower limb involvement|Hereditary sensory and autonomic neuropathy type 7
  • rs114854233Uncertain significancesingle nucleotide variantFamilial episodic pain syndrome with predominantly lower limb involvement|Hereditary sensory and autonomic neuropathy type 7
  • rs201107889Uncertain significancesingle nucleotide variantFamilial episodic pain syndrome with predominantly lower limb involvement|Hereditary sensory and autonomic neuropathy type 7|Charcot-Marie-Tooth disease|Hereditary motor neuron disease

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.