Gene entry
RRM2B
ribonucleotide reductase regulatory TP53 inducible subunit M2B
- Chromosome
- 8
- Cytoband
- 8q22.3
- Variants (rsID)
- 6
RRM2B is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 8 (region 8q22.3). Its official name is “ribonucleotide reductase regulatory TP53 inducible subunit M2B”. The reference table lists 6 variants (rsID) for this gene.
Clinically classified variants
2 reference-table entries with clinical significance.
- rs28999710Benignsingle nucleotide variantProgressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 5|Mitochondrial DNA depletion syndrome 8a
- rs515726184Likely pathogenicDeletionMitochondrial DNA depletion syndrome 8a|RRM2B-related mitochondrial disease|Idiopathic camptocormia
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.