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Gene entry

RAD51C

RAD51 paralog C

Chromosome
17
Cytoband
17q22
Variants (rsID)
25

RAD51C is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 17 (region 17q22). Its official name is “RAD51 paralog C”. The reference table lists 25 variants (rsID) for this gene.

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Clinically classified variants

23 reference-table entries with clinical significance.

  • rs28363317Benignsingle nucleotide variantFanconi anemia complementation group O|Hereditary cancer-predisposing syndrome|Fanconi anemia|Breast and Ovarian Cancer Susceptibility|Breast-ovarian cancer, familial, susceptibility to, 3|Malignant tumor of breast|Hereditary breast ovarian cancer syndrome|Breast and/or ovarian cancer
  • rs45511291Benignsingle nucleotide variantFanconi anemia complementation group O|Hereditary cancer-predisposing syndrome|Fanconi anemia|Breast and Ovarian Cancer Susceptibility|Breast-ovarian cancer, familial, susceptibility to, 3|Malignant tumor of breast
  • rs147241704Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Breast-ovarian cancer, familial, susceptibility to, 3|Breast-ovarian cancer, familial, susceptibility to, 3|Fanconi anemia complementation group O|Hereditary breast ovarian cancer syndrome|Fanconi anemia complementation group O|Malignant tumor of breast|Breast and/or ovarian cancer|Familial cancer of breast
  • rs149228565Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O
  • rs201079501Conflicting interpretationssingle nucleotide variantFanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3|Hereditary cancer-predisposing syndrome|Breast-ovarian cancer, familial, susceptibility to, 3|Fanconi anemia complementation group O
  • rs376403182Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O
  • rs587780256Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3|Malignant tumor of breast
  • rs587782332Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O
  • rs730881929Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O|Fanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3
  • rs786203249Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3
  • rs759292615Likely pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O
  • rs1060502601PathogenicDeletionFanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3|Fanconi anemia complementation group O|Hereditary breast ovarian cancer syndrome|Hereditary cancer-predisposing syndrome
  • rs200293302Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3|Fanconi anemia complementation group O|Hereditary breast ovarian cancer syndrome|RAD51C-Related Disorders|Breast carcinoma|Breast-ovarian cancer, familial, susceptibility to, 3
  • rs267606997Pathogenicsingle nucleotide variantFanconi anemia complementation group O|Hereditary cancer-predisposing syndrome|Hereditary breast ovarian cancer syndrome
  • rs267606999Pathogenicsingle nucleotide variantBreast-ovarian cancer, familial, susceptibility to, 3|Hereditary cancer-predisposing syndrome|Fanconi anemia complementation group O|Fanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3
  • rs587781287Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3
  • rs587782818Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3|Fanconi anemia complementation group O|Malignant tumor of breast
  • rs757128712Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O
  • rs760235677Pathogenicsingle nucleotide variantBreast-ovarian cancer, familial, susceptibility to, 3|Hereditary cancer-predisposing syndrome|Neoplasm of ovary|Fanconi anemia complementation group O
  • rs767796996Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O|Hereditary breast ovarian cancer syndrome
  • rs779582317Pathogenicsingle nucleotide variantFanconi anemia complementation group O|Hereditary cancer-predisposing syndrome|Hereditary breast ovarian cancer syndrome
  • rs876659874Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Fanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3|Fanconi anemia complementation group O|Breast-ovarian cancer, familial, susceptibility to, 3
  • rs200857129Uncertain significancesingle nucleotide variantHereditary cancer-predisposing syndrome|Breast-ovarian cancer, familial, susceptibility to, 3|Fanconi anemia complementation group O|Hereditary breast ovarian cancer syndrome

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.