Gene entry
PTPN22
protein tyrosine phosphatase non-receptor type 22
- Chromosome
- 1
- Cytoband
- 1p13.2
- Variants (rsID)
- 8
PTPN22 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 1 (region 1p13.2). Its official name is “protein tyrosine phosphatase non-receptor type 22”. The reference table lists 8 variants (rsID) for this gene.
Clinically classified variants
2 reference-table entries with clinical significance.
- rs2476601Benignsingle nucleotide variantDiabetes mellitus, insulin-dependent, susceptibility to|Rheumatoid arthritis|Systemic lupus erythematosus, susceptibility to|Hashimoto thyroiditis, susceptibility to|Addison disease, susceptibility to|chronic fatigue syndrome with infection-triggered onset
- rs56048322Uncertain significancesingle nucleotide variant
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.