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Gene entry

PRKN

parkin RBR E3 ubiquitin protein ligase

Chromosome
6
Cytoband
6q26
Variants (rsID)
382

PRKN is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 6 (region 6q26). Its official name is “parkin RBR E3 ubiquitin protein ligase”. The reference table lists 382 variants (rsID) for this gene.

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Clinically classified variants

9 reference-table entries with clinical significance.

  • rs1801474Benignsingle nucleotide variantAutosomal recessive juvenile Parkinson disease 2
  • rs56092260Benignsingle nucleotide variantAutosomal recessive juvenile Parkinson disease 2
  • rs75860381Benignsingle nucleotide variantAutosomal recessive juvenile Parkinson disease 2
  • rs149953814Conflicting interpretationssingle nucleotide variantAutosomal recessive juvenile Parkinson disease 2
  • rs55774500Conflicting interpretationssingle nucleotide variantAutosomal recessive juvenile Parkinson disease 2
  • rs137853054Pathogenicsingle nucleotide variantAutosomal recessive juvenile Parkinson disease 2
  • rs137853058Pathogenicsingle nucleotide variantAutosomal recessive juvenile Parkinson disease 2
  • rs137853060Pathogenicsingle nucleotide variantAutosomal recessive juvenile Parkinson disease 2
  • rs34424986Pathogenicsingle nucleotide variantAutosomal recessive juvenile Parkinson disease 2|Young-onset Parkinson disease|Lung carcinoma|Neoplasm of ovary|Leprosy, susceptibility to, 2|Autosomal recessive juvenile Parkinson disease 2|See cases

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.