Gene entry
NEXN
nexilin F-actin binding protein
- Chromosome
- 1
- Cytoband
- 1p31.1
- Variants (rsID)
- 20
NEXN is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 1 (region 1p31.1). Its official name is “nexilin F-actin binding protein”. The reference table lists 20 variants (rsID) for this gene.
Clinically classified variants
15 reference-table entries with clinical significance.
- rs1166698Benignsingle nucleotide variantCardiovascular phenotype|Hypertrophic cardiomyopathy 20|Dilated cardiomyopathy 1CC
- rs188416492Benignsingle nucleotide variantHypertrophic cardiomyopathy 20|Dilated cardiomyopathy 1CC
- rs201171783Benignsingle nucleotide variantHypertrophic cardiomyopathy 20|Dilated cardiomyopathy 1CC|Cardiovascular phenotype|Cardiomyopathy
- rs201763096Benignsingle nucleotide variantHypertrophic cardiomyopathy 20|Dilated cardiomyopathy 1CC|Cardiovascular phenotype|Cardiomyopathy|Premature ventricular contraction
- rs35366555Benignsingle nucleotide variantDilated cardiomyopathy 1CC|Hypertrophic cardiomyopathy 20|Cardiovascular phenotype|Cardiomyopathy
- rs369897647Benignsingle nucleotide variantCardiomyopathy|Hypertrophic cardiomyopathy 20|Dilated cardiomyopathy 1CC
- rs374260457Benignsingle nucleotide variantHypertrophic cardiomyopathy 20|Dilated cardiomyopathy 1CC|Cardiovascular phenotype
- rs559464457Benignsingle nucleotide variantDilated cardiomyopathy 1CC|Hypertrophic cardiomyopathy 20|Cardiomyopathy
- rs137853197Conflicting interpretationssingle nucleotide variantDilated cardiomyopathy 1CC|Primary dilated cardiomyopathy|Hypertrophic cardiomyopathy 20|Dilated cardiomyopathy 1CC|Cardiovascular phenotype|Dilated cardiomyopathy 1S|Cardiomyopathy
- rs146245480Conflicting interpretationssingle nucleotide variantHypertrophic cardiomyopathy 20|Primary familial hypertrophic cardiomyopathy|Hypertrophic cardiomyopathy 20|Dilated cardiomyopathy 1CC|Cardiomyopathy
- rs372065024Conflicting interpretationssingle nucleotide variantDilated cardiomyopathy 1CC|Hypertrophic cardiomyopathy 20|Cardiovascular phenotype|Cardiomyopathy
- rs727505353Conflicting interpretationssingle nucleotide variantPrimary dilated cardiomyopathy|Dilated cardiomyopathy 1CC|Hypertrophic cardiomyopathy 20
- rs201447781Uncertain significancesingle nucleotide variantHypertrophic cardiomyopathy 20|Dilated cardiomyopathy 1CC|Cardiomyopathy
- rs372532824Uncertain significancesingle nucleotide variant
- rs397517858Uncertain significancesingle nucleotide variantDilated cardiomyopathy 1CC|Hypertrophic cardiomyopathy 20
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.