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Gene entry

NDUFS8

NADH:ubiquinone oxidoreductase core subunit S8

Chromosome
11
Cytoband
11q13.2
Variants (rsID)
6

NDUFS8 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 11 (region 11q13.2). Its official name is “NADH:ubiquinone oxidoreductase core subunit S8”. The reference table lists 6 variants (rsID) for this gene.

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Clinically classified variants

4 reference-table entries with clinical significance.

  • rs149201273Conflicting interpretationssingle nucleotide variantLeigh syndrome|Mitochondrial complex I deficiency, nuclear type 1
  • rs1804688Conflicting interpretationssingle nucleotide variantMitochondrial complex I deficiency, nuclear type 1|Leigh syndrome
  • rs121912638Uncertain significancesingle nucleotide variantMitochondrial complex 1 deficiency, nuclear type 2
  • rs369602258Uncertain significancesingle nucleotide variantMitochondrial complex I deficiency|Leigh syndrome

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.