Gene entry
NDUFS3
NADH:ubiquinone oxidoreductase core subunit S3
- Chromosome
- 11
- Cytoband
- 11p11.2
- Variants (rsID)
- 7
NDUFS3 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 11 (region 11p11.2). Its official name is “NADH:ubiquinone oxidoreductase core subunit S3”. The reference table lists 7 variants (rsID) for this gene.
Clinically classified variants
5 reference-table entries with clinical significance.
- rs11039306Conflicting interpretationssingle nucleotide variantLeigh syndrome|Mitochondrial complex I deficiency, nuclear type 1
- rs368907187Conflicting interpretationssingle nucleotide variantLeigh syndrome|Mitochondrial complex I deficiency, nuclear type 1
- rs104894270Likely pathogenicsingle nucleotide variantMitochondrial complex 1 deficiency, nuclear type 8
- rs28939714Pathogenicsingle nucleotide variantMitochondrial complex 1 deficiency, nuclear type 8|Neurodevelopmental delay
- rs376722149Uncertain significancesingle nucleotide variant
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.