Gene entry
MYOC
myocilin
- Chromosome
- 1
- Cytoband
- 1q24.3
- Variants (rsID)
- 17
MYOC is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 1 (region 1q24.3). Its official name is “myocilin”. The reference table lists 17 variants (rsID) for this gene.
Clinically classified variants
7 reference-table entries with clinical significance.
- rs61730974Benignsingle nucleotide variantGlaucoma|Glaucoma 1, open angle, A|Glaucoma of childhood
- rs200208925Likely benignsingle nucleotide variantMYOC-Related Disorders|Glaucoma of childhood
- rs74315339Likely benignsingle nucleotide variantGlaucoma 3, primary congenital, a, digenic|Glaucoma 1, open angle, A|MYOC-Related Disorders|Glaucoma of childhood
- rs28936694Pathogenicsingle nucleotide variantGlaucoma 1, open angle, a, digenic
- rs74315329Pathogenicsingle nucleotide variantGlaucoma 1, open angle, A|Primary open angle glaucoma|6 conditions|Glaucoma of childhood
- rs74315330Pathogenicsingle nucleotide variantGlaucoma 1, open angle, A|Glaucoma of childhood
- rs74315334Pathogenicsingle nucleotide variantGlaucoma 1, open angle, A|Glaucoma of childhood
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.