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Gene entry

MYH6

myosin heavy chain 6

Chromosome
14
Cytoband
14q11.2
Variants (rsID)
63

MYH6 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 14 (region 14q11.2). Its official name is “myosin heavy chain 6”. The reference table lists 63 variants (rsID) for this gene.

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Clinically classified variants

55 reference-table entries with clinical significance.

  • rs141014719Benignsingle nucleotide variantCardiovascular phenotype|Hypertrophic cardiomyopathy 14|Cardiomyopathy
  • rs145566711Benignsingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiomyopathy
  • rs148091079Benignsingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiovascular phenotype|Cardiomyopathy
  • rs150574114Benignsingle nucleotide variantCardiovascular phenotype|Hypertrophic cardiomyopathy 14|Cardiomyopathy
  • rs178637Benignsingle nucleotide variant
  • rs183611755Benignsingle nucleotide variantCardiovascular phenotype|Cardiomyopathy
  • rs190342289Benignsingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs193283041Benignsingle nucleotide variantCardiovascular phenotype|Hypertrophic cardiomyopathy 14|Cardiomyopathy
  • rs193922653Benignsingle nucleotide variantCardiomyopathy|Primary dilated cardiomyopathy|Hypertrophic cardiomyopathy 14
  • rs200854143Benignsingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiovascular phenotype|Cardiomyopathy
  • rs201016285Benignsingle nucleotide variantCardiovascular phenotype|Hypertrophic cardiomyopathy 14|Cardiomyopathy
  • rs28711516Benignsingle nucleotide variantCardiovascular phenotype|Hypertrophic cardiomyopathy 14
  • rs28730764Benignsingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs28730765Benignsingle nucleotide variantCardiomyopathy|Hypertrophic cardiomyopathy 14
  • rs28730771Benignsingle nucleotide variantCardiovascular phenotype|Cardiomyopathy|Hypertrophic cardiomyopathy 14
  • rs28730772Benignsingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiovascular phenotype|Atrial septal defect 3|Dilated cardiomyopathy 1EE|Cardiomyopathy
  • rs34935550Benignsingle nucleotide variantCardiovascular phenotype|Cardiomyopathy|Restrictive cardiomyopathy|Hypertrophic cardiomyopathy|Hypertrophic cardiomyopathy 14
  • rs365990Benignsingle nucleotide variantCardiovascular phenotype|Hypertrophic cardiomyopathy 14
  • rs367866050Benignsingle nucleotide variantHypertrophic cardiomyopathy|Hypertrophic cardiomyopathy 14
  • rs376527296Benignsingle nucleotide variantCardiovascular phenotype|Cardiomyopathy|Hypertrophic cardiomyopathy 14
  • rs452036Benignsingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs557113705Benignsingle nucleotide variantCardiomyopathy|Hypertrophic cardiomyopathy 14
  • rs58131640Benignsingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiomyopathy
  • rs61742472Benignsingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiovascular phenotype|Cardiomyopathy
  • rs77679218Benignsingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiovascular phenotype|Cardiomyopathy
  • rs140660481Conflicting interpretationssingle nucleotide variantCardiomyopathy|Brugada syndrome|Hypertrophic cardiomyopathy|Left ventricular noncompaction cardiomyopathy|Hypertrophic cardiomyopathy 14|Hypertrophic cardiomyopathy 1
  • rs142992009Conflicting interpretationssingle nucleotide variantPrimary familial hypertrophic cardiomyopathy|Inborn genetic diseases|Hypertrophic cardiomyopathy 14|Cardiomyopathy
  • rs143978652Conflicting interpretationssingle nucleotide variantDilated cardiomyopathy 1EE|Primary dilated cardiomyopathy|Hypertrophic cardiomyopathy 14|Sudden cardiac death|Hypertrophic cardiomyopathy 14|Cardiovascular phenotype|Primary familial hypertrophic cardiomyopathy|Wolff-Parkinson-White pattern|Cardiomyopathy|Primary dilated cardiomyopathy|Ventricular tachycardia
  • rs144571463Conflicting interpretationssingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiovascular phenotype|Cardiomyopathy
  • rs145508517Conflicting interpretationssingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs145611185Conflicting interpretationssingle nucleotide variantPrimary familial hypertrophic cardiomyopathy|Hypertrophic cardiomyopathy 14|Cardiomyopathy
  • rs199859986Conflicting interpretationssingle nucleotide variantPrimary familial hypertrophic cardiomyopathy|Hypertrophic cardiomyopathy 14|Cardiovascular phenotype|Cardiomyopathy
  • rs200153625Conflicting interpretationssingle nucleotide variantPrimary familial hypertrophic cardiomyopathy|Hypertrophic cardiomyopathy 14
  • rs200662317Conflicting interpretationssingle nucleotide variantCardiovascular phenotype|Hypertrophic cardiomyopathy 14|Cardiomyopathy
  • rs200883903Conflicting interpretationssingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs201193346Conflicting interpretationssingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiomyopathy|Primary dilated cardiomyopathy
  • rs201327273Conflicting interpretationssingle nucleotide variantPrimary dilated cardiomyopathy|Primary familial dilated cardiomyopathy|Hypertrophic cardiomyopathy 14
  • rs267606904Conflicting interpretationssingle nucleotide variantHypertrophic cardiomyopathy 14|Hypertrophic cardiomyopathy|Hemiplegia|Primary dilated cardiomyopathy|Migraine
  • rs34330111Conflicting interpretationssingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiovascular phenotype|Primary familial hypertrophic cardiomyopathy|Cardiomyopathy
  • rs374941865Conflicting interpretationssingle nucleotide variant
  • rs139886074Likely benignsingle nucleotide variantCardiovascular phenotype|Hypertrophic cardiomyopathy 14
  • rs148407931Likely benignsingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs182373896Likely benignsingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs186134696Likely benignsingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs201411075Likely benignsingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs367742240Likely benignsingle nucleotide variant
  • rs368183862Likely benignsingle nucleotide variantHypertrophic cardiomyopathy 14|Cardiomyopathy
  • rs368588052Likely benignsingle nucleotide variantPrimary familial hypertrophic cardiomyopathy|Hypertrophic cardiomyopathy 14
  • rs371661383Likely benignsingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs141534763Uncertain significancesingle nucleotide variantCardiovascular phenotype
  • rs150415679Uncertain significancesingle nucleotide variantCardiovascular phenotype|Hypertrophic cardiomyopathy 14|Hypertrophic cardiomyopathy 1|Atrial septal defect 3
  • rs188023690Uncertain significancesingle nucleotide variantCardiovascular phenotype
  • rs200925880Uncertain significancesingle nucleotide variantHypertrophic cardiomyopathy 14
  • rs267606905Uncertain significancesingle nucleotide variantDilated cardiomyopathy 1EE|Hypertrophic cardiomyopathy 14|Primary familial hypertrophic cardiomyopathy
  • rs267606907Uncertain significancesingle nucleotide variantHypertrophic cardiomyopathy 14

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.