Gene entry
MUTYH
mutY DNA glycosylase
- Chromosome
- 1
- Cytoband
- 1p34.1
- Variants (rsID)
- 96
MUTYH is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 1 (region 1p34.1). Its official name is “mutY DNA glycosylase”. The reference table lists 96 variants (rsID) for this gene.
Clinically classified variants
89 reference-table entries with clinical significance.
- rs139977567Benignsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome|Carcinoma of colon
- rs3219484Benignsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome|Breast carcinoma|Carcinoma of colon
- rs3219485Benignsingle nucleotide variant
- rs3219496Benignsingle nucleotide variantHereditary cancer-predisposing syndrome|Carcinoma of colon|Familial adenomatous polyposis 2
- rs1057517765Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome|Carcinoma of colon
- rs1060504205Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2
- rs138089183Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs140288388Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs144616312Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs149866955Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs150792276Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Carcinoma of colon
- rs200165598Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs201412035Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs201678305Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs35352891Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs367908623Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs372673338Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs376600220Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs558173961Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs587780742Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs587781864Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs730881838Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs750592289Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Familial cancer of breast|Breast carcinoma
- rs751875215Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs75321043Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Carcinoma of colon
- rs766553845Conflicting interpretationsDeletionFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs77542170Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome|Gastric cancer|Carcinoma of colon
- rs786202141Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs786203213Conflicting interpretationsDeletionHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs79777494Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Carcinoma of colon
- rs864622450Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs879254257Conflicting interpretationssingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs767717597Likely benignsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs1057517459Likely pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2
- rs1057520660Likely pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs1060501333Likely pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2
- rs1064793198Likely pathogenicsingle nucleotide variant
- rs1383826978Likely pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs587781337Likely pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs786203161Likely pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs864621967Likely pathogenicDeletionHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs876659420Likely pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs876660837Likely pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome
- rs1057517457PathogenicDeletionFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs1060501321Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2
- rs1060501324Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs1060501335Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs1060501336PathogenicDeletionFamilial adenomatous polyposis 2
- rs1064795480PathogenicDeletionFamilial adenomatous polyposis 2
- rs1064795596Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2
- rs121908381Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome|Carcinoma of colon
- rs121908383Pathogenicsingle nucleotide variantGastric cancer
- rs1338038953Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2
- rs140342925Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Pilomatrixoma|Neoplasm of stomach|Familial adenomatous polyposis 2|Breast carcinoma|Carcinoma of colon
- rs143353451Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs200495564Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome|Familial colorectal cancer
- rs34126013Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs34612342Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Endometrial carcinoma|Hereditary cancer-predisposing syndrome|Carcinoma of colon|Pilomatrixoma|Familial adenomatous polyposis 2|Neoplasm of stomach|Gastric cancer|See cases
- rs36053993Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Endometrial cancer|Hereditary cancer-predisposing syndrome|Carcinoma of colon|Familial adenomatous polyposis 2|Neoplasm of stomach|Small intestine carcinoid|Colorectal adenomatous polyposis, autosomal recessive, with pilomatricomas|Pilomatrixoma|Familial adenomatous polyposis 2|Neoplasm of stomach|Ovarian carcinoma|Breast carcinoma|Colon cancer|Familial colorectal cancer|See cases
- rs370124822Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs372267274Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs374950566Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Carcinoma of colon|Breast carcinoma
- rs376561094Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs587778541PathogenicMicrosatelliteHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Breast carcinoma|Colorectal polyposis
- rs587780078PathogenicDuplicationHereditary cancer-predisposing syndrome|Carcinoma of colon|Familial adenomatous polyposis 2
- rs587780088Pathogenicsingle nucleotide variantCarcinoma of colon|Familial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Pilomatrixoma|Neoplasm of stomach
- rs587781295Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs587781338Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs587782730Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs587783057Pathogenicsingle nucleotide variantCarcinoma of colon|Familial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome|Breast carcinoma|Familial colorectal cancer
- rs745921592Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs762307622Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Carcinoma of colon
- rs766420907Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs781222233PathogenicDeletionFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome|Colonic neoplasm
- rs863224452Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2
- rs863224502Pathogenicsingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs876659625Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome
- rs876659676Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Carcinoma of colon
- rs876660190PathogenicDuplicationHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs876660774Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs876660787Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs878854189PathogenicDuplicationFamilial adenomatous polyposis 2
- rs886039606PathogenicDeletionFamilial adenomatous polyposis 2
- rs121908382Uncertain significancesingle nucleotide variantGastric cancer|Familial adenomatous polyposis 2
- rs1331273811Uncertain significancesingle nucleotide variantHereditary cancer-predisposing syndrome
- rs147923905Uncertain significancesingle nucleotide variantFamilial adenomatous polyposis 2|Hereditary cancer-predisposing syndrome
- rs200229669Uncertain significancesingle nucleotide variantCarcinoma of colon|Hereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2|Pilomatrixoma|Neoplasm of stomach|Familial adenomatous polyposis 2
- rs376790729Uncertain significancesingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
- rs587782263Uncertain significancesingle nucleotide variantHereditary cancer-predisposing syndrome|Familial adenomatous polyposis 2
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.