Gene entry
MSH3
mutS homolog 3
- Chromosome
- 5
- Cytoband
- 5q14.1
- Variants (rsID)
- 40
MSH3 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 5 (region 5q14.1). Its official name is “mutS homolog 3”. The reference table lists 40 variants (rsID) for this gene.
Clinically classified variants
6 reference-table entries with clinical significance.
- rs1650697Benignsingle nucleotide variantHereditary cancer-predisposing syndrome|Constitutional megaloblastic anemia with severe neurologic disease
- rs26279Benignmissense_variant&splice_region_variantThyroid Carcinoma|Cutaneous Telangiectasia and Cancer Syndrome, Familial|Tumor Predisposition Syndrome|Inherited Cancer-Predisposing Syndrome|Myotonic Dystrophy 1|Male Infertility|Azoospermia|Hepatocellular Carcinoma|Infertility|Squamous Cell Carcinoma|Prostate Cancer|Lynch Syndrome
- rs115198722Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Endometrial carcinoma|Familial adenomatous polyposis 4
- rs187411724Uncertain significancesingle nucleotide variantHereditary cancer-predisposing syndrome
- rs188074706Uncertain significancesingle nucleotide variantHereditary cancer-predisposing syndrome
- rs201216791Uncertain significancesingle nucleotide variantHereditary cancer-predisposing syndrome
Other listed variants
- rs28058
- rs32951
- rs32985
- rs1346464
- rs1650685
- rs1677647
- rs1805355
- rs2448492
- rs3797886
- rs6151626
- rs6151628
- rs6151742
- rs6151744
- rs6151780
- rs6151816
- rs6151838
- rs6151874
- rs6151928
- rs10570342
- rs72765589
- rs74588959
- rs75119252
- rs76249824
- rs76850449
- rs114819297
- rs114948303
- rs115394556
- rs116152815
- rs116383327
- rs138339194
- rs186924833
- rs187398147
- rs190723980
- rs191755538
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.