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Gene entry

MLH3

mutL homolog 3

Chromosome
14
Cytoband
14q24.3
Variants (rsID)
32

MLH3 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 14 (region 14q24.3). Its official name is “mutL homolog 3”. The reference table lists 32 variants (rsID) for this gene.

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Clinically classified variants

23 reference-table entries with clinical significance.

  • rs141066164Benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs149962294Benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs17782839Benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs28756981Benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs28756982Benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs28756986Benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs28756989Benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs28756993Benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs372912259Benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs61755655Benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs142124529Conflicting interpretationssingle nucleotide variantLynch syndrome|Colorectal cancer, hereditary nonpolyposis, type 7
  • rs144707485Conflicting interpretationssingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs28756978Conflicting interpretationssingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs28939071Conflicting interpretationssingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs143278116Likely benignsingle nucleotide variantColorectal cancer, non-polyposis|Colorectal cancer, hereditary nonpolyposis, type 7
  • rs28756979Likely benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs61754769Likely benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs77687901Likely benignsingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs151133595Uncertain significancesingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs200350079Uncertain significancesingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs201721635Uncertain significancesingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs201931206Uncertain significancesingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7
  • rs28937870Uncertain significancesingle nucleotide variantColorectal cancer, hereditary nonpolyposis, type 7

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.