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Gene entry

MLC1

modulator of VRAC current 1

Chromosome
22
Cytoband
22q13.33
Variants (rsID)
13

MLC1 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 22 (region 22q13.33). Its official name is “modulator of VRAC current 1”. The reference table lists 13 variants (rsID) for this gene.

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Clinically classified variants

5 reference-table entries with clinical significance.

  • rs2294384Benignsingle nucleotide variantMegalencephalic leukoencephalopathy with subcortical cysts 1
  • rs41302601Benignsingle nucleotide variantMegalencephalic leukoencephalopathy with subcortical cysts 1|Megalencephalic leukoencephalopathy with subcortical cysts
  • rs121908345Pathogenicsingle nucleotide variantMegalencephalic leukoencephalopathy with subcortical cysts 1|Megalencephalic leukoencephalopathy with subcortical cysts
  • rs80358242Pathogenicsingle nucleotide variantMegalencephalic leukoencephalopathy with subcortical cysts 1|Megalencephalic leukoencephalopathy with subcortical cysts
  • rs80358245Pathogenicsingle nucleotide variantMegalencephalic leukoencephalopathy with subcortical cysts 1

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.