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Gene entry

MGMT

O-6-methylguanine-DNA methyltransferase

Chromosome
10
Cytoband
10q26.3
Variants (rsID)
84

MGMT is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 10 (region 10q26.3). Its official name is “O-6-methylguanine-DNA methyltransferase”. The reference table lists 84 variants (rsID) for this gene.

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Clinically classified variants

3 reference-table entries with clinical significance.

  • rs12917Not classifiedmissense_variantLymphoma, Hodgkin, Classic|Lymphoma|Glioma|Glial Tumor|Diffuse Large B-Cell Lymphoma|Follicular Lymphoma|B-Cell Lymphoma|Pancytopenia|Prostate Cancer|Neutropenia|Thrombocytopenia|Glioblastoma|Lymphoma, Non-Hodgkin, Familial|Squamous Cell Carcinoma|Gallbladder Disease 1|Colorectal Cancer|Myelodysplastic Syndrome|Gallbladder Cancer
  • rs2308321Not classifiedmissense_variantDiffuse Large B-Cell Lymphoma|Lymphoma, Non-Hodgkin, Familial|Pancytopenia|Prostate Cancer|Neutropenia|Thrombocytopenia|Follicular Lymphoma|Myelodysplastic Syndrome|Lymphoma, Hodgkin, Classic|Glioma|Glioblastoma|B-Cell Lymphoma|Glial Tumor
  • rs2308327Not classifiedmissense_variantProstate Cancer|Diffuse Large B-Cell Lymphoma|Lymphoma, Non-Hodgkin, Familial|Pancytopenia|Neutropenia|Thrombocytopenia|Follicular Lymphoma|Lung Cancer|Myelodysplastic Syndrome|Lymphoma, Hodgkin, Classic|Glioma|Glioblastoma|B-Cell Lymphoma|Glial Tumor

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.