Gene entry
MEN1
menin 1
- Chromosome
- 11
- Cytoband
- 11q13.1
- Variants (rsID)
- 99
MEN1 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 11 (region 11q13.1). Its official name is “menin 1”. The reference table lists 99 variants (rsID) for this gene.
Clinically classified variants
97 reference-table entries with clinical significance.
- rs138770431Conflicting interpretationssingle nucleotide variantMultiple endocrine neoplasia, type 1|Hyperparathyroidism|Hereditary cancer-predisposing syndrome
- rs141679530Conflicting interpretationssingle nucleotide variantMultiple endocrine neoplasia, type 1|Hyperparathyroidism|Hereditary cancer-predisposing syndrome
- rs143329068Conflicting interpretationssingle nucleotide variantHyperparathyroidism|Multiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs2959656Conflicting interpretationssingle nucleotide variantPrimary hyperparathyroidism|Multiple endocrine neoplasia, type 1
- rs373669288Conflicting interpretationssingle nucleotide variantMultiple endocrine neoplasia, type 1|Multiple endocrine neoplasia|Hyperparathyroidism|Hereditary cancer-predisposing syndrome
- rs374659656Conflicting interpretationssingle nucleotide variantHyperparathyroidism|Multiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs374749001Conflicting interpretationssingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs607969Conflicting interpretationssingle nucleotide variantMultiple endocrine neoplasia, type 1|Multiple endocrine neoplasia|Hereditary cancer-predisposing syndrome|Hyperparathyroidism
- rs764290037Conflicting interpretationsMicrosatelliteMultiple endocrine neoplasia, type 1
- rs77461664Conflicting interpretationssingle nucleotide variantMultiple endocrine neoplasia, type 1|Hyperparathyroidism|Hereditary cancer-predisposing syndrome
- rs794728634Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|Multiple endocrine neoplasia, type 1
- rs794728661Conflicting interpretationsMicrosatelliteMultiple endocrine neoplasia, type 1
- rs1060503789Likely benignsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs999121619Likely benignsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs1057521110Likely pathogenicsingle nucleotide variant
- rs1057524571Likely pathogenicsingle nucleotide variant
- rs1064793167Likely pathogenicsingle nucleotide variant
- rs1064793169Likely pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome
- rs1064793398Likely pathogenicsingle nucleotide variant
- rs1064795635Likely pathogenicDeletion
- rs386134245Likely pathogenicDuplicationMultiple endocrine neoplasia, type 1
- rs386134249Likely pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs386134254Likely pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs386134255Likely pathogenicInsertionMultiple endocrine neoplasia, type 1
- rs386134261Likely pathogenicDuplicationMultiple endocrine neoplasia, type 1
- rs794728618Likely pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome
- rs104894256Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs104894257Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs104894258Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs104894259Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs104894260Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs104894261Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome|Metastatic pancreatic neuroendocrine tumours
- rs104894262Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs104894263Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs104894265Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs104894266Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs1057518572Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Multiple endocrine neoplasia, type 1
- rs1057520733Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs1060499974Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs1060499976Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs1060499987Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs1060499990PathogenicDeletionMultiple endocrine neoplasia, type 1
- rs1060499991Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs1060499992Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs1064793613PathogenicDeletion
- rs1064793672Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Multiple endocrine neoplasia, type 1
- rs1114167483PathogenicDuplicationHereditary cancer-predisposing syndrome
- rs121913034Pathogenicsingle nucleotide variantAngiofibroma, somatic
- rs121913035Pathogenicsingle nucleotide variantAdrenocortical adenoma
- rs28931612Pathogenicsingle nucleotide variantParathyroid adenoma, somatic|Multiple endocrine neoplasia, type 1
- rs376872829Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Multiple endocrine neoplasia, type 1
- rs386134250Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs386134251PathogenicDeletionMultiple endocrine neoplasia, type 1
- rs386134256Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs386134260Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs398124436PathogenicDuplication
- rs587776841PathogenicDeletionLipoma, somatic|Multiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs750904332Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs794728616Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Multiple endocrine neoplasia, type 1
- rs794728622Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs794728629Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs794728631Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Multiple endocrine neoplasia, type 1
- rs794728632Pathogenicsingle nucleotide variant
- rs794728636PathogenicInsertion
- rs794728637PathogenicDeletion
- rs794728638PathogenicDuplication
- rs794728640PathogenicDeletionMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs794728643PathogenicDeletion
- rs794728645PathogenicDeletion
- rs794728647Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Multiple endocrine neoplasia, type 1
- rs794728648Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs794728654Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs794728655PathogenicDeletion
- rs794728656PathogenicDuplication
- rs794728657PathogenicMicrosatelliteMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs794728658PathogenicDeletionHereditary cancer-predisposing syndrome
- rs863223311Pathogenicsingle nucleotide variantHyperparathyroidism 1
- rs863224526Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs863224527Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs864622615Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs869025185PathogenicDeletionMultiple endocrine neoplasia, type 1|Hereditary cancer-predisposing syndrome
- rs869312167PathogenicDeletionPrimary hyperparathyroidism
- rs878855191PathogenicDeletionMultiple endocrine neoplasia, type 1
- rs878855192Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs878855196PathogenicDeletionMultiple endocrine neoplasia, type 1
- rs886039414Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Multiple endocrine neoplasia, type 1
- rs886039415Pathogenicsingle nucleotide variantHereditary cancer-predisposing syndrome|Multiple endocrine neoplasia, type 1
- rs886039416Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs886039419Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs886039420PathogenicDeletionHereditary cancer-predisposing syndrome
- rs886039421PathogenicDeletion
- rs886039553Pathogenicsingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs886041213PathogenicDuplicationHereditary cancer-predisposing syndrome|Multiple endocrine neoplasia, type 1
- rs886041214PathogenicDuplication
- rs886042035Pathogenicsingle nucleotide variant
- rs104894268Uncertain significancesingle nucleotide variantMultiple endocrine neoplasia, type 1
- rs386134248Uncertain significanceDeletionMultiple endocrine neoplasia, type 1
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.