Gene entry
LEPR
leptin receptor
- Chromosome
- 1
- Cytoband
- 1p31.3
- Variants (rsID)
- 62
LEPR is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 1 (region 1p31.3). Its official name is “leptin receptor”. The reference table lists 62 variants (rsID) for this gene.
Clinically classified variants
7 reference-table entries with clinical significance.
- rs1137101Benignsingle nucleotide variantLEPTIN RECEPTOR POLYMORPHISM|Obesity due to leptin receptor gene deficiency|Monogenic Non-Syndromic Obesity
- rs1805094Benignsingle nucleotide variantLEPTIN RECEPTOR POLYMORPHISM|Monogenic Non-Syndromic Obesity|Obesity due to leptin receptor gene deficiency
- rs1805096Benignsingle nucleotide variantObesity due to leptin receptor gene deficiency|Monogenic Non-Syndromic Obesity
- rs1805134Benignsingle nucleotide variantMonogenic Non-Syndromic Obesity|Obesity due to leptin receptor gene deficiency
- rs61781316Conflicting interpretationssingle nucleotide variantObesity|Obesity due to leptin receptor gene deficiency|Monogenic Non-Syndromic Obesity
- rs193922650Likely pathogenicsingle nucleotide variantObesity
- rs144159890Pathogenicsingle nucleotide variantLEPR-Related Disorders|Obesity due to leptin receptor gene deficiency
Other listed variants
- rs970467
- rs1045895
- rs1171278
- rs1177681
- rs1782754
- rs1892534
- rs2025803
- rs2025804
- rs2104564
- rs2767485
- rs4567312
- rs4606347
- rs4655723
- rs6700896
- rs7413467
- rs9436301
- rs9436746
- rs9436748
- rs10128072
- rs10749753
- rs10789188
- rs10889551
- rs10889569
- rs11208648
- rs11208659
- rs12035604
- rs12038998
- rs12059300
- rs12077210
- rs12135802
- rs12145690
- rs13306523
- rs17097193
- rs17127656
- rs17127673
- rs17412347
- rs60948573
- rs61781283
- rs72683113
- rs74082072
- rs74986928
- rs75148473
- rs75417229
- rs77451629
- rs77715828
- rs77838365
- rs78650744
- rs78862345
- rs79843967
- rs111573261
- rs114280901
- rs117291834
- rs150025527
- rs180693002
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.