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Gene entry

LDB3

LIM domain binding 3

Chromosome
10
Cytoband
10q23.2
Variants (rsID)
57

LDB3 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 10 (region 10q23.2). Its official name is “LIM domain binding 3”. The reference table lists 57 variants (rsID) for this gene.

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Clinically classified variants

27 reference-table entries with clinical significance.

  • rs146265188Benignsingle nucleotide variantCardiovascular phenotype|Primary dilated cardiomyopathy|Myofibrillar myopathy 4
  • rs201693259Benignsingle nucleotide variantMyofibrillar myopathy 4
  • rs34423165Benignsingle nucleotide variantCardiomyopathy|Myofibrillar myopathy 4|Dilated Cardiomyopathy, Dominant|Myofibrillar Myopathy, Dominant|Left ventricular noncompaction cardiomyopathy|Cardiovascular phenotype|Dilated cardiomyopathy 1C
  • rs121908333Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 4|Cardiomyopathy
  • rs121908334Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 4|Neuromuscular disease|Myofibrillar myopathy|Cardiomyopathy|Dilated cardiomyopathy 1C
  • rs121908338Conflicting interpretationssingle nucleotide variantDilated cardiomyopathy 1C|Primary dilated cardiomyopathy|Myofibrillar myopathy 4|Cardiovascular phenotype
  • rs138251566Conflicting interpretationssingle nucleotide variantPrimary dilated cardiomyopathy|Cardiovascular phenotype|Cardiomyopathy|Hypertrophic cardiomyopathy|Myofibrillar myopathy 4|Dilated cardiomyopathy 1A
  • rs143764931Conflicting interpretationssingle nucleotide variantCardiomyopathy|Myofibrillar myopathy 4
  • rs200796750Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 4|Hypertrophic cardiomyopathy
  • rs371708921Conflicting interpretationssingle nucleotide variantMyofibrillar Myopathy, Dominant|Dilated Cardiomyopathy, Dominant|Myofibrillar myopathy 4|Left ventricular noncompaction cardiomyopathy
  • rs372331627Conflicting interpretationssingle nucleotide variantArrhythmogenic right ventricular cardiomyopathy|Myofibrillar myopathy 4|Cardiomyopathy
  • rs373632943Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 4|Cardiovascular phenotype
  • rs375306400Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 4
  • rs45487699Conflicting interpretationssingle nucleotide variantDilated cardiomyopathy 1C|Familial hypertrophic cardiomyopathy 24|Myofibrillar myopathy 4|Cardiovascular phenotype|Dilated cardiomyopathy 1A|Cardiomyopathy
  • rs45521338Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 4
  • rs45529531Conflicting interpretationssingle nucleotide variantCardiomyopathy|Dilated Cardiomyopathy, Dominant|Left ventricular noncompaction cardiomyopathy|Myofibrillar Myopathy, Dominant|Myofibrillar myopathy 4|Cardiovascular phenotype
  • rs45577134Conflicting interpretationssingle nucleotide variantPrimary dilated cardiomyopathy|Myofibrillar myopathy 4|Cardiovascular phenotype|Cardiomyopathy
  • rs71473272Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 4|Dilated Cardiomyopathy, Dominant|Myofibrillar Myopathy, Dominant|Left ventricular noncompaction cardiomyopathy|Cardiovascular phenotype|Dilated cardiomyopathy 1C
  • rs727503126Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 4
  • rs754704023Conflicting interpretationssingle nucleotide variantDilated Cardiomyopathy, Dominant|Myofibrillar Myopathy, Dominant|Myofibrillar myopathy 4|Left ventricular noncompaction cardiomyopathy
  • rs77304928Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 4
  • rs140552419Likely benignsingle nucleotide variantMyofibrillar myopathy 4|Cardiovascular phenotype
  • rs121908335Uncertain significancesingle nucleotide variantMyofibrillar myopathy 4|Cardiovascular phenotype|Cardiomyopathy|Dilated cardiomyopathy 1C|Primary familial dilated cardiomyopathy
  • rs141870580Uncertain significancesingle nucleotide variantMyofibrillar myopathy 4|Cardiovascular phenotype|Primary familial dilated cardiomyopathy
  • rs145983824Uncertain significancesingle nucleotide variantFamilial hypertrophic cardiomyopathy 24|Myofibrillar myopathy 4
  • rs201786090Uncertain significancesingle nucleotide variantMyofibrillar myopathy 4
  • rs45514002Uncertain significancesingle nucleotide variantDilated cardiomyopathy 1C|Left ventricular noncompaction 3|Myofibrillar myopathy 4

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.