Gene entry
LAMP2
lysosome associated membrane protein 2
- Chromosome
- X
- Cytoband
- Xq24
- Variants (rsID)
- 27
LAMP2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome X (region Xq24). Its official name is “lysosome associated membrane protein 2”. The reference table lists 27 variants (rsID) for this gene.
Clinically classified variants
19 reference-table entries with clinical significance.
- rs141541387Benignsingle nucleotide variantCardiovascular phenotype|Danon disease|History of neurodevelopmental disorder
- rs2748Benignsingle nucleotide variantDanon disease|Hypertrophic cardiomyopathy
- rs375341409Benignsingle nucleotide variantTrifascicular block on electrocardiogram|Danon disease
- rs5957381Benignsingle nucleotide variantDanon disease|Hypertrophic cardiomyopathy
- rs138991195Conflicting interpretationssingle nucleotide variantCardiovascular phenotype|History of neurodevelopmental disorder|Hypertrophic cardiomyopathy|Danon disease|Cardiomyopathy
- rs141574558Conflicting interpretationssingle nucleotide variantDanon disease
- rs147369153Conflicting interpretationssingle nucleotide variantCardiovascular phenotype|Danon disease|Hypertrophic cardiomyopathy|History of neurodevelopmental disorder|Cardiomyopathy
- rs149276836Conflicting interpretationssingle nucleotide variantDanon disease|Cardiomyopathy
- rs201030806Conflicting interpretationssingle nucleotide variantHypertrophic cardiomyopathy|Danon disease|Cardiovascular phenotype
- rs193922649Likely pathogenicDeletionPrimary familial hypertrophic cardiomyopathy|Danon disease
- rs397516738Likely pathogenicDeletionHypertrophic cardiomyopathy
- rs397516739Likely pathogenicDuplicationHypertrophic cardiomyopathy
- rs397516752Likely pathogenicsingle nucleotide variantHypertrophic cardiomyopathy
- rs104894858Pathogenicsingle nucleotide variantDanon disease|Hypertrophic cardiomyopathy|Danon disease
- rs137852527Pathogenicsingle nucleotide variantDanon disease
- rs397516751PathogenicDeletionDanon disease|Hypertrophic cardiomyopathy
- rs727503119Pathogenicsingle nucleotide variantDanon disease
- rs727503120Pathogenicsingle nucleotide variantDanon disease|Hypertrophic cardiomyopathy
- rs200297370Uncertain significancesingle nucleotide variant
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.